The main therapeutic goal of ulcerative colitis (uc) is to induce and maintain remission to prevent long term disease progression. treat to target strategies, first introduced by the stride consensus and updated in 2021, have shifted focus from symptomatic control toward more stringent objective endpoints. today, patient monitoring should be based on a combination of biomarkers and clinical. The main therapeutic goal of ulcerative colitis (uc) is to induce and maintain remission to prevent long term disease progression. treat to target strategies, first introduced by the stride consensus and updated in 2021, have shifted focus from symptomatic control toward more stringent objective endpoints. today, patient monitoring should be.
Introduction. ulcerative colitis (uc) is a chronic inflammatory and progressive disease with relapsing episodes. the course of the disease varies from asymptomatic, mild to extensive inflammation of the colon, resulting in disability, intestinal damage, permanent fibrosis, and the need for surgery [ 1 ]. approximately 10–20% of uc patients. Historically, medical therapy for ulcerative colitis (uc) was limited to corticosteroids. excitingly, over the past just 1–2 decades, the options for medical therapy have expanded and include biologics and small molecules, with more agents actively being developed. in this article, we review the current and emerging treatment strategies for uc stratified according to disease severity. The main goals of ulcerative colitis (uc) treatment are to both induce and maintain the clinical and endoscopic remission of disease, reduce the incidence of complications such as dysplasia and colorectal carcinoma and improve quality of life. although a curative medical treatment for uc has not yet been found, new therapeutic strategies addressing specific pathogenetic mechanisms of disease. Ulcerative colitis (uc) is a chronic inflammatory disorder defined by mucosal inflammation that involves the colon and rectum in a continuous pattern [ 1, 2, 3 ]. the peak age of onset is 30–40 years old, and men and women are affected equally [ 4 ]. while still not yet fully defined, the pathogenesis of uc is multifactorial and implicates.
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