Figure 2 From The Role Of Magnesium In Neurological Disorders Potential prevention and treatment of neurological disorders. current literature is reviewed for. migraine, chronic pain, epilepsy, alzheimer’s, parkinson’s, and stroke, as well as the. Future research examining the role of magnesium in pd should include measurements of magnesium concentrations in the cerebral spinal fluid (csf) (as a measure of magnesium in the central nervous system), rather than solely in the periphery. this measurement technique may be of use in other neurological disorders as well.
A Mini Review On The Various Facets Effecting Brain Delivery Of The role of magnesium in neurological disorders. anna e. kirkland, g. sarlo, kathleen f. holton. published in nutrients 1 june 2018. medicine. tldr. overall, the mechanistic attributes of magnesium in neurological diseases connote the macromineral as a potential target for neurological disease prevention and treatment. From a neurological standpoint, magnesium plays an essential role in nerve transmission and neuromuscular conduction. it also functions in a protective role against excessive excitation that can lead to neuronal cell death (excitotoxicity), and has been implicated in multiple neurological disorders. due to these important functions within the. Moreover, because of the growing interest in the implications of trpm7, a cation channel with kinase function, in neurological and neurodegenerative disorders, there is a need to better understand the role of this channel in the direct (on target cells) or indirect (e.g., via systemic inflammation) impact on nervous system alterations. Figure 1. glutamatergic n methyl d aspartate receptor with magnesium block of calcium channel. reprinted from [8] with permission from elsevier. "the role of magnesium in neurological disorders".